In running, the main cause of knee injury is heel striking because it alters your entire stride to the extent where more collisional and compressive impacts pry into the knee, and was also found to increase the degenerative process of the joint, regardless of the amount of under-heel cushioning in a shoe! This is not the case in forefoot running, which has gained universal acclaim as the cure for chronic knee injury.
Heel strike running causes chronic injury because of the heel-to-toe rollover action of the foot that occurs after heel strike was found to produce the highest jolt, jarring, jerky, braking and loading forces that cannot be reducible by cushioned running shoes, but with forefoot running only.
When it comes to preventing running-related heel injuries, running shoes with thick cushioned heels were found to actually cause pain and injury to the heel by causing you to land too hard on your heels. The most clinically promising method to protect your heels when running is to adopt a forefoot strike landing which was found to spread impact best over the foot, resulting little to no damaging impact at the heel.
Heel strike running was found to be a big risk factor for shin splints and fracture by causing a functional loss of impact absorption in the knee, while causing too much force-intensive stop and go (i.e. too much intense braking) as compared with forefoot running, which was found to do a better job at improving knee flexion, thereby reducing dangerous loads to the shins.
Heel strike running was found to be produce repetitive trauma impacts and joint overloading to the knees and hips as compared with forefoot running, which was found to prevent all forms of impact from rising to injury-predisposing levels.
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