Research shows if you run barefoot on harder surfaces, the only way it can be done most safely is if a forefoot strike is used, not heel strike. Because forefoot running eliminates the burst in collisional impact, reduces high brake forces while reducing all-around impact forces, allows anyone who runs barefoot to run safely on the hardest of surfaces.
The only way to reassuringly protect your knees long-term from running is not with thicker cushioned running shoes, or a knee brace, but with paying close attention to where you land on your foot when you run. You must avoid heel strike at all costs because this landing style engages other mechanics that inflict higher net-forces on the knee. Instead, you need to land on your forefoot because it has been proven to the most good at sustainable reducing and preventing the impact variables and mechanics responsible for destroying the knee-joint.
The best foot strike technique for running is the forefoot strike because it reduces nearly all the forms of impact linked to injury, even if you run barefoot on the hardest surface, you will not produce any more impact if you land forefoot-first. Conversly, landing heel-first sets off a shockwave that damages the shins, knees and even lower back!
There are major differences between minimalist and normal running shoes which include the barefoot-feel of minimalist running shoes were found to do a better job at increasing the likelihood of avoiding a force intensive-heel strike, and instead, encourages a forefoot strike landing tied to significantly lower instantaneous loading and vertical impact peaks as compared to normal cushioned running shoes.
The safest, most efficient way to run uphill is to land with a forefoot strike because it was found to do a better job at improving the position of both initial foot strike position and your upper body posture in ways that greatly reduces the opposing forces linked to most common running-related injuries as compared with heel striking.
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